Bulgarian researchers create new method for tracking chromosomes

published on 4/17/25 12:41 PM

Photo: Bulgarian Academy of Sciences

Bulgarian young researchers have made an impressive scientific discovery in the field of cell biology. A Bulgarian team has published a scientific paper in which they track human chromosomes during mitosis, which was previously considered impossible.

The scientific paper, titled “Supra-second tracking and live-cell karyotyping reveal principles of mitotic chromosome dynamics,” has not only attracted the attention of one of the most renowned and influential journals, Nature Cell Biology, but has also been featured on the cover of the journal, the Bulgarian Academy of Sciences and the Ministry of Education announced.

The new method, called FAST CHIMP (Facilitated Segmentation and Tracking of Chromosomes in Mitosis Pipeline), uses a combination of super-resolution microscopy and deep machine tracking, providing unprecedented accuracy in monitoring rapidly rearranging chromosomes in real time.

The first author of the article is the doctoral student Rumen Stamatov, who graduated with a master's degree from Duke University and a bachelor's degree from the University of Pennsylvania. The scientific supervisor is Assoc. Prof. Stoyno Stoynov. The project involves postdoctoral student Sonya Uzunova from the Institute of Molecular Biology and students from Sofia University Ioana Kicheva, Tavian Blagoev and Maria Karaboeva.

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Bulgarian researchers create new method for tracking chromosomes

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